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Weaning off lexapro weight loss medication, the medication is still working. "We haven't lost the weight off," said Dr. Mark Stiles, of the Indiana State Department Health. "It's not even close to being a weight loss medication. Instead it has become an appetite suppressant." Dr. Stiles added that Lexapro also isn't working to slow weight gain in those who have already lost the weight. "It's not even close to being a weight loss medication. Instead it has become an appetite suppressant. "We're going to keep using these meds on patients until we have an obesity treatment that's shown to be successful." He said the weight gain is usually caused by eating too much sugar rather than simply taking the medication. About 7% of Lexapro-treated patients lost weight, he said. But even if it still doesn't seem to be working, some doctors continue to recommend Lexapro in patients with a history of dieting. Dr. Mark T. Leiter, director of the Center for Health Policy and Behavioral Research at the New York Presbyterian Hospital, said doctors need more information. "It is common for drugs to lose efficacy," he said. "These medications are marketed to treat only weight-stable patients w